Pure Evil villains who are girls or women.
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A
- Abaddon (Supernatural)
- Abigail Williams (The Crucible)
- Adrianna de la Santos
- Agatha Trunchbull
- Ahmanet
- Ai Magase
- Airachnid
- Akasha (The Vampire Chronicles)
- Alexia Ashford
- Alice (Tales of Halloween)
- Alina Gray
- Alison Wallace
- Alphys (Negativetale)
- Amy Hughes
- Aparoid Queen
- Apollyon
- Arba
- Arte and Pollo (SupaMame)
- Audrey Redheart
- Aunt Ruth Chandler
- The Avatar (Red Flood)
- Aya Tokoyogi
B
C
- Captain Phasma
- Carol and Dylan's Mother
- Cassandra Nova
- Catalina
- Catherine de Medici
- Catherine Ortiz
- Chara (DulcetRefrain)
- Chara (Frisk vs Chara, Undertale animation)
- Chara (Kanon version)
- Chara (Stronger Than You)
- Chara (The Indie Game Movie)
- Charlotte Ermengarde
- Christabella
- Cipher (Fast & Furious)
- Claire Wyden
- Constance Hatchaway
- Corrine Dollanganger
- Cosmos
- Countess Rajine
- Cruella de Vil
D
E
G
H
J
K
L
M
- Madame Lorraine
- Madison Bell
- Magdalena
- Magnolia Costa Leitão
- Manager of the Princess Imperial
- Mandy Lane
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- Margaret Booth
- Mari (Hands)
- Marian Mallon
- Marissa Wiegler
- Mary Elnor
- Mary Keeny
- Mary Kelley
- Mary Piggy
- Mary Shaw
- Matriarch Babel Tanit
- Medea Pideth Machina
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- Medusa (Legend Quest)
- Medusa (Percy Jackson and the Lightning Thief)
- Medusa Gorgon
- Megicula
- Melisha Tweedy
- Mirage
- Mirror Queen
- Misaki
- Miss Gribben
- Missy Armitage
- Monika (Madame Macabre)
- Monika (The Stupendium)
- Mother Apollonia
- Mother Sphere
- Mrs. Kawabe
- Mrs. Packerton
- Mugan
O